An Intel Pentium 4 2.00GHz CPU is required at a minimum to run Rogue Rails. The cheapest graphics card you can play it on is an NVIDIA GeForce 6200. Rogue Rails system requirements state that you will need at least 4 GB of RAM. In terms of game file size, you will need at least 500 MB of free disk space available.
Rogue Rails will run on PC system with Windows XP, 7, and 10 (32-bit or 64-bit) and upwards.