Provided that you have at least an NVIDIA GeForce 6200 graphics card you can play the game. To play Upside Down you will need a minimum CPU equivalent to an Intel Pentium 4 2.00GHz. Upside Down system requirements state that you will need at least 1 GB of RAM. You will need at least 600 MB of free disk space to install Upside Down.
Upside Down will run on PC system with Windows XP or Later and upwards. Additionally it has Mac and Linux versions.