An Intel Pentium 4 2.00GHz CPU is required at a minimum to run Antitetrise. The minimum memory requirement for Antitetrise is 256 MB of RAM installed in your computer. The cheapest graphics card you can play it on is an NVIDIA GeForce 6100. In terms of game file size, you will need at least 15 MB of free disk space available.
Antitetrise will run on PC system with 7, 8, 10 and upwards.