Provided that you have at least an NVIDIA GeForce 7600 GS graphics card you can play the game. You will need at least 300 MB of free disk space to install Telophase. An Intel Core 2 Duo E6320 CPU is required at a minimum to run Telophase. The minimum memory requirement for Telophase is 2 GB of RAM installed in your computer.
Telophase will run on PC system with Windows 10 and upwards. Additionally it has a Mac version.