The cheapest graphics card you can play it on is an NVIDIA GeForce 6200. In terms of game file size, you will need at least 256 MB of free disk space available. An Intel Pentium 4 2.00GHz CPU is required at a minimum to run GetMeBro!. GetMeBro! system requirements state that you will need at least 512 MB of RAM.
GetMeBro! will run on PC system with Windows XP SP2+ and upwards. Additionally it has a Mac version.