Provided that you have at least an NVIDIA GeForce GTX 460 graphics card you can play the game. An Intel Core 2 Duo T7250 CPU is required at a minimum to run 222. 222 system requirements state that you will need at least 4 GB of RAM. In terms of game file size, you will need at least 4 GB of free disk space available.
222 will run on PC system with Windows 7 and upwards.