Provided that you have at least an NVIDIA GeForce 6200 graphics card you can play the game. An Intel Pentium 4 2.00GHz CPU is required at a minimum to run 2048. 2048 system requirements state that you will need at least 512 MB of RAM. You will need at least 512 MB of free disk space to install 2048.
2048 will run on PC system with Windows Vista 32-bit/64-bit and upwards. Additionally it has a Linux version.