DepthMera system requirements state that you will need at least 2 GB of RAM. An Intel Pentium 4 2.00GHz CPU is required at a minimum to run DepthMera. The cheapest graphics card you can play it on is an NVIDIA GeForce 510. In terms of game file size, you will need at least 450 MB of free disk space available.
DepthMera will run on PC system with Windows XP (SP 2,3), Vista, 7, 8, 10 and upwards. Additionally it has a Mac version.