The cheapest graphics card you can play it on is an NVIDIA GeForce GTX 970. NatureFly system requirements state that you will need at least 8 GB of RAM. An Intel Core i5-4590 CPU is required at a minimum to run NatureFly. In terms of game file size, you will need at least 300 MB of free disk space available.
NatureFly will run on PC system with windows 7 and upwards.