In terms of game file size, you will need at least 9 GB of free disk space available. The minimum memory requirement for Those Who Remain is 4 GB of RAM installed in your computer. Additionally, the game developers recommend somewhere around 8 GB of RAM in your system. The cheapest graphics card you can play it on is an ATI Radeon HD 5750. Futhermore, an ATI Radeon HD 5970 is recommended in order to run Those Who Remain with the highest settings. An Intel Core 2 Duo E8400 CPU is required at a minimum to run Those Who Remain.
Those Who Remain will run on PC system with Windows Vista 64-bit and upwards. Additionally it has a Mac version.